脑卒中急性期抑郁障碍汉密尔顿抑郁量表各因子分的特点

目的:脑卒中抑郁障碍(post-strokedepression,PSD)是脑卒中后常见情感障碍,先前的研究显示PSD的发生与社会、心理及生物学因素有关,但对脑卒中急性期PSD的发生率及汉密尔顿抑郁量表(Hamiltondepressionscale,HAMD)各因子分的改变特征尚缺乏研究。本研究旨在了解脑脑卒中急性期PSD的发生率及HAMD各因子分的特征。方法:选择98例住院诊断为脑卒中急性期患者作为研究对象,除评定一般自然状况外,采用ICD-10F06.32器质性抑郁障碍诊断标准及HAMD对入组患者进行评定,对所有患者进行颅脑CT扫描。结果:脑卒中急性期PSD的发生率为42%。脑卒中急性期PSD组与非抑郁组的HAMD各因子分比较有明显差异,脑卒中急性期轻型PSD组与中、重型组HAMD各因子分比较有明显差异。结论:脑卒中急性期PSD的发病率较高,脑卒中急性期PSD的HAMD总分及各因子分较非抑郁组均有改变;脑卒中急性期PSD的轻型组与中重型组在HAMD各因子分之间有明显差异。

Factor scale characteristic of Hamilton depression scale of post-stroke depression in acute phase

AIM:Post stroke depression(PSD) is a commonly seen affective disorder after stroke. It is indicated in previous study that the occurrence of PSD have relations with social, psychologic and biologic factors, but the reseach in aspect of incidence rate of PSD and the change characteristic of every factor of Hamilton depression scale (HAMD) in acute phase is scarce. This study aims at getting the message about incidence rate of PSD and change characteristic of every factor of Hamilton depression scale (HAMD) in acute phase.METHODS:To select 98 patients who were in acute phase of post stroke according to admission diagnosis as reseach object and evaluate selected patients with ICD 10 F06.32 organic depressive disorder diagnosis standard and HAMD except for general nature status. CT scan to head for all patients were performed. RESULTS:The incidence rate of PSD in acute phase was 42%.Analysis indicated there were obvious differences on scale of every factor of HAMD between PSD group and nondepression group in acute phase and so were between mild PSD group and moderate,severe PSD group. CONCLUSION:The incidence rate of PSD in acute phase is higher.The total scale and factor scale of HAMD have changed compared with nondepression group,there were obvious differences in factor scale of HAMD between mild PSD group and moderate,severe PSD group.