| 血管生成抑制蛋白vasohibin的研究进展 |
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| 引用本文： | 王芳,白怀. 血管生成抑制蛋白vasohibin的研究进展[J]. 基础医学与临床, 2011, 31(10) |
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| 作者姓名： | 王芳 白怀 |
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| 作者单位： | 四川大学华西第二医院遗传代谢性疾病及围生医学实验室,四川成都,610041 |
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| 摘 要： | 血管新生参与机体重要的生理和病理过程。Vasohibin是新近发现的调节血管生成的内皮源性负反馈调节因子,对抑制血管生成起重要作用。Vasohibin因参与肿瘤﹑视网膜疾病及类风湿性关节炎等血管新生异常疾病的发生发展而备受关注,相关研究可望为探索这些疾病的发生机制以及寻找新的治疗措施奠定基础。
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| 关 键 词： | vasohibin VEGF 血管生成 |
Advances on angiogenesis inhibitor vasohibin |
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| WANG Fang,BAI Huai. Advances on angiogenesis inhibitor vasohibin[J]. Basic Medical Sciences and Clinics, 2011, 31(10) |
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| Authors: | WANG Fang BAI Huai |
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| Affiliation: | WANG Fang,BAI Huai(Laboratory of Genetic Disease and Perinatal Medicine,West China Second University Hospital,Sichuan University,Chengdu 610041,China) |
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| Abstract: | Angiogenesis can occur under physiological as well as pathological conditions.Vasohibin is a novel endothelium-derived negative feedback regulator of angiogenesis and plays an important role in the inhibition of angiogenesis,which may have impact on the process of tumor growth,retinopathy,rheumatoid arthritis.The study in the related area has great potential for understanding the mechanistic causes of the diseases and has important implications for the development of novel therapeutic strategies. |
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| Keywords: | vasohibin VEGF angiogenesis |
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