| HPLC同时测定银黄含化片中绿原酸和黄芩苷含量 |
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| 引用本文： | 刘梅娟,王玉芬,伏光华. HPLC同时测定银黄含化片中绿原酸和黄芩苷含量[J]. 齐鲁药事, 2005, 24(4): 213-214 |
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| 作者姓名： | 刘梅娟 王玉芬 伏光华 |
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| 作者单位： | 1. 临沂市妇幼保健院,临沂,276001
2. 临沂市药品检验所,临沂,276001 |
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| 摘 要： | 目的 建立HPLC法测定银黄含化片中绿原酸和黄芩苷含量的方法。方法 采用ODS色普柱(25 0mm×4 . 6mm,5 μm),以乙腈- 1%磷酸溶液为流动相进行梯度洗脱,检测波长为316nm。结果 绿原酸、黄芩苷分别在0 . 0 2mg·ml-1～0 . 19mg·ml-1和0 . 1mg·ml-1～0 . 8mg·ml-1浓度范围内呈良好线性关系,平均回收率分别为97. 3%和98. 6 %。结论 方法准确、灵敏,回收率高,可用于该制剂的质量控制
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| 关 键 词： | HPLC 银黄含化片 绿原酸 黄芩苷 |
| 文章编号： | 1672-7738(2005)04-0213-02 |
Determination of Chlorogenic acid and Baicalin in Inhuang Tablets by HPLC |
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| Liu Mei-juan,Wang Yu-fen,Fu Guang-hua. Determination of Chlorogenic acid and Baicalin in Inhuang Tablets by HPLC[J]. qilu pharmaceutical affairs, 2005, 24(4): 213-214 |
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| Authors: | Liu Mei-juan Wang Yu-fen Fu Guang-hua |
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| Affiliation: | Liu Mei-juan,Wang Yu-fen,Fu Guang-hua1 |
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| Abstract: | Objective To determine the contents of Chlorogenic acid and Baicalin in Inhuang Tablets.Methods ODS column was used.The mobile phase was acetonitrile-0.1%H_3PO_4 solution with detective wavelength of 316nm.Results The linear ranges of Chlorogenic acid and Baicalin were respectively in 0.02～0.19mg·ml -1 and 0.1～0.8mg·ml -1.The average recoveries were 97.3% and 98.6%.Conclusion The method was accurate and sensitive with a good recovery. |
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| Keywords: | HPLC Inhuang Tablets Chlorogenic acid Baicalin |
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