宫颈不典型鳞状细胞217例临床分析

目的探讨宫颈不典型鳞状细胞（ASCUS）的临床意义。方法对细胞学诊断为ASCUS的患者行高危型人乳头瘤病毒（HR-HPV）DNA检测，分为HR—HPV阳性组和HR—HPV阴性组进行观察。两组均进行阴道镜下活检，以组织学诊断为依据，比较ASCUS中HR—HPV阳性组和阴性组CIN发生率的差异。结果217例ASCUS中HR—HPV阳性的134例（61．6％），HR—HPV阴性的83例（38．2％），这两组中CIN的发生率分别为30．6％和7．2％（P〈0．05）；CIN2—3的发生率分别为8．9％和1．2％（P〈0．05）。结论对ASCUS的患者应及时行HR—HPVDNA检测，HR—HPV阳性者行阴道镜下活检，HR—HPV阴性者可随访，及早发现宫颈癌前病变和宫颈癌，避免延误病情。

The clinical analysis of 217 cases with cervical atypical squamous cells .

Objective To explore the clinical significamce of cervical atypical squamous cells The ASCUS cytology patients were with high- risk human papillomavirus （HR-HPV） （ASCUS） . DNA testing. HR-HPV- positive group and HR-HPV-negative group were observed.Both groups were carried out colposcopic biopsy to diagnose based on histology, comparison of the differences in the incidence of CIN between HR-HPV- positive group and negative group.Results In 217 cases of ASCUS, the results of HR-HPV positive were 134 cases （61.6%） , HR- HPV- negative 83 cases （38.2%） , the incidence of CIN were 30.6% and 7.2% （P 〈0.05） Conclusion The patients with ASCUS should be with HR-HPV DNA testing, the HR-HPV-positive should be with biopsy under colposcopy, the HR-HPV-negative should be followed up, in order to early detect cervical precancerous lesions and cervical cancer.