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肝动脉栓塞化疗结合无水酒精注射治疗中晚期原发性肝癌疗效分析
作者姓名:QUZengqiang  QIANGuojun  CHENHan
作者单位:DepartmentofIntervention,EasternHepatobiliarySurgeryHospital,SecondMilitaryMedicalUniversity,Shanghai200438,China
摘    要:Objective:To evaluate the clinical efficacy of the combined treatment with transcatheter arterial chemoembolization (TACE) and percutaneous ethanol injection (PEI) on hepatocellular carcinoma (HCC). Methods:312 patients with moderate or advanced HCCs were divided into two groups: 170 cases underwent TACE treatment alone, 142 cases were treated with TACE and PEI under B-ultrasotmd guidance. Results:The rates of reduction in tumor diameter and the decline in serum AFP level were 41.2% and 40.4% in the TACE group and 75.4% and 74.1% in the TACE PEI group respectively. The 6, 12 and 24 months survival rates in the TACE group were 77.1%,34.1% and 18.8%,respectively and in the TACE PEI group 87.3%, 62.0% and 38.0%, respectively. Overall, there was a significant difference between the two treatment groups (P<0.05). Conclusion:Treatment on HCCs with TACE PEI is convenient, safe and results in better survival rates than TACE alone.

关 键 词:TACE  HCC  PEI  AFP
收稿时间:14 January 2002

Therapeutic effect of transcatheter arterial chemoembolization combined with percutaneous ethanol injection in hepatocellular carcinoma
QUZengqiang QIANGuojun CHENHan.Therapeutic effect of transcatheter arterial chemoembolization combined with percutaneous ethanol injection in hepatocellular carcinoma[J].The Chinese-German Journal of Clinical Oncology,2002,1(1):28-29.
Authors:Qu Zengqiang  Qian Guojun  Chen Han
Institution:(1) Department of Intervention, Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, 200438 Shanghai, China
Abstract:Objective To evaluate the clinical efficacy of the combined treatment with transcatheter arterial chemoembolization (TACE) and percutaneous ethanol injection (PEI) on hepatocellular carcinoma (HCC). Methods 312 patients with moderate or advanced HCCs were divided into two groups: 170 cases underwent TACE treatment alone, 142 cases were treated with TACE and PEI under B-ultrasound guidance. Results The rates of reduction in tumor diameter and the decline in serum AFP level were 41.2% and 40.4% in the TACE group and 75.4% and 74.1% in the TACE + PEI group respectively. The 6,12 and 24 months survival rates in the TACE group were 77.1%, 34,1% and 18.8%, respectively and in the TACE + PEI group 87.3%, 62.0% and 38.0%, respectively. Overall, there was a significant difference between the two treatment groups (P<0.05). Conclusion Treatment on HCCs with TACE + PEI is convenient, safe and results in better survival rates than TACE alone.
Keywords:neoplasm hepatocellular  embolization  ethanol  ultrasound guided intervention
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