Study of the hemostatic properties of gaseous ozone |
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| Authors: | Yu. P. Kashperskii A. A. Adamyan V. A. Makarov S. P. Glyantsev V. A. Zhukov |
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| Affiliation: | (1) State Center for Surgical Dressings, Sutures, and Polymer Materials, A. V. Vishnevskii Institute of Surgery, Russian Academy of Medical Sciences, Moscow;(2) Department of Pathology and Pharmacology of Hemostasis, Hematology Research Center, Russian Academy of Medical Sciences, Moscow |
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| Abstract: | The hemostatic properties of ozone were studied on models of parenchymatous (from a wound in the liver) and stem (from the stump of the tail) bleedings in rats. An air-ozone mixture at a flow rate of 1 liter/min and a concentration of 2 mg/ml was found to exert a pronounced hemostatic effect. Our findings indicate that the arrest of bleeding under the influence of ozone is due to the formation of a fibrin membrane on the surface of the flowing blood, this leading to rapid and effective hemostasis. Preliminary drying of the wound still further speeds the onset of hemostasis. Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 120 N o 7 pp. 62–65, July, 1995 Presented by D. S. Sarkisov, Member of the Russian Academy of Medical Sciences |
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| Keywords: | gaseous ozone parenchymatous bleeding stem bleeding hemostasis rats |
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