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Comparison of sufentanil/propofol versus isoflurane/nitrous oxide anaesthesia on mesenteric artery blood flow
Authors:J H M J Zwijsen  MD  Consultant  J G Bovill  MD  PhD  FFARCSI  Professor    R H Geelkerken  MD  Consultant  T A Delahunt  J H van Bockel  MD  PhD    J Hermans  PhD  
Institution:Department of Anaesthesiology, University Hospital Leiden, PO Box 9600, 2300 RC Leiden, The Netherlands.;Department of Surgery, University Hospital Leiden, PO Box 9600, 2300 RC Leiden, The Netherlands.;Department of Medical Statistics, University Hospital Leiden, PO Box 9600, 2300 RC Leiden, The Netherlands.
Abstract:Duplex sonography was used to determine the changes in mesenteric arterial blood flow occurring in patients undergoing aortic surgery, anaesthetised either by total intravenous anaesthesia with propofol and sufentanil (group A) or inhalational anaesthesia with isoflurane and nitrous oxide (group B). Sixteen patients were studied. Measurements were performed immediately before and 15 min after induction of anaesthesia, before surgery. There was a 38% decrease (p = 0.015) in the superior mesenteric artery end diastolic velocity in group A and a 23% decrease (p = 0.033) in the superior mesenteric artery peak systolic velocity in group B. There were no changes in any of the other sonography parameters in either group. We conclude that neither total intravenous anaesthesia with propofol and sufentanil nor inhalational anaesthesia with isoflurane and nitrous oxide have any clinically significant influence on mesenteric blood flow in the absence of surgical stimulation.
Keywords:Anaesthetic techniques            inhalational  total intravenous              Blood            flow  mesenteric              Measurement techniques            duplex sonography
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