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| 肾宁片质量标准研究 | |
| 引用本文： | 张文清,叶华,张怡评.肾宁片质量标准研究[J].中国药房,2008,19(30):2365-2367. |
| 作者姓名： | 张文清 叶华 张怡评 |
| 作者单位： | 1. 福建省级机关医院,福州市,350003 2. 福建省中医学院附属第二人民医院,福州市,350003 3. 国家海洋局第三海洋研究所,厦门市,361005 |
| 摘 要： | 目的:建立肾宁片的质量标准。方法:采用薄层色谱(TLC)法对肾宁片中益母草、大黄、栀子、黄柏进行定性鉴别;采用高效液相色谱法测定栀子苷、芍药苷的含量。结果:TLC可鉴别出益母草、大黄、栀子、黄柏相对应的斑点。栀子苷、芍药苷的进样量分别在0.032 2～0.386 4μg(r=0.999 9)、0.041～0.492μg(r=0.999 9)范围内与各自峰面积积分值呈良好的线性关系;二者平均回收率分别为101.09%、100.08%,RSD分别为0.54%(n=6)、1.28%(n=6)。结论:所建标准可用于肾宁片的质量控制。 |
| 关 键 词： | 肾宁片 质量标准 薄层色谱法 高效液相色谱法 |
Study on Quality Standard for Shenning Tablet |
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| ZHANG Wen-qing,YE Hua,ZHANG Yi-ping.Study on Quality Standard for Shenning Tablet[J].China Pharmacy,2008,19(30):2365-2367. | |
| Authors: | ZHANG Wen-qing YE Hua ZHANG Yi-ping |
| Institution: | ZHANG Wen-qing,YE Hua,ZHANG Yi-ping(Fujian Provincial Institution Hospital,Fuzhou 350003,China;The Second People＇s Hospital Affiliated to Fujian College of Traditional Chinese Medicine,Fuzhou 350003, China;State Oceanic Administration Third Institute of Oceanography, Xiamen 361005, China) |
| Abstract: | OBJECTIVE： To establish a quality standard for Shenning tablet.METHODS： Leonurus japonicus, Radix et Rhizoma Rhei, Gardenia jasminoides, Phellodendron chinense in Shenning tablet was identified by TLC.The contents of Jasminoidin and Peoniflorin in Shenning tablet were determined by HPLC.RESULTS：The relevant spots in Leonurus japonicus, Radix et Rhizoma Rhei, Gardenia jasminoides, Phellodendron chinense were identified by TLC.The linear ranges of Jasminoidin and Peoniflorin were 0.032 2-0. 386 4 μg（ r = 0. 999 9） and 0.041-0.492μg（ r = 0.999 9）, respecctively, with average recovery rates at 101.09 % and 100.08 %, respectively and RSD at 0.54% and 1.28%, respectively （ n = 6） . CONCLUSION ： The established quality standard is suitable for the quality control of Shenning tablet. |
| Keywords: | Shenning tablet Quality standard TLC HPLC |
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