Heparin-induced thrombocytopenia and thrombosis: reversal with streptokinase. A case report and review of literature |
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| Authors: | D P Mehta E L Yoder J Appel K L Bergsman |
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| Institution: | Department of Internal Medicine, Grace Hospital, Wayne State University School of Medicine, Detroit, Michigan. |
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| Abstract: | Heparin-induced thrombocytopenia and thrombosis is associated with a significant incidence of morbidity and mortality. Prompt recognition of this complication and immediate withdrawal of heparin therapy are imperative. This report describes a case of heparin-induced thrombosis and thrombocytopenia with major vascular insufficiency of the extremities. This is the first reported instance of the use of intravenous streptokinase for the treatment of heparin-induced venous thrombosis. |
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| Keywords: | heparin thrombocytopenia thrombosis streptokinase |
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