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连续性血液净化治疗在多脏器功能障碍综合征治疗中的应用分析
引用本文:王勤学,董晓辉. 连续性血液净化治疗在多脏器功能障碍综合征治疗中的应用分析[J]. 国际医药卫生导报, 2016, 0(2): 210-213. DOI: 10.3760/cma.j.issn.1007-1245.2016.02.022
作者姓名:王勤学  董晓辉
作者单位:266300,胶州市人民医院血液净化中心
摘    要:目的 观察及分析对多脏器功能障碍综合征(MODS)患者采用连续性血液净化治疗的临床疗效,旨在为临床治疗提供有效依据.方法 本组收集2010年3月至2015年3月间我院ICU接诊的40例MODS患者进行临床研究,均给予连续性血液净化治疗,观察及记录治疗前后本组患者的血流动力学指数、急性生理与慢性健康评分(APACHEⅡ评分)及血管内皮细胞功能指数等指标的变化情况,并对治疗前后进行.结果 40例患者治疗后的CV、HR指标明显低于治疗前(P<0.05),MAP、CI指标明显高于治疗前(P<0.05);治疗后的Hcy、ET-1指标明显低于治疗前(P<0.05),NO指标明显高于治疗前(P<0.05);治疗后患者的APACHEⅡ评分明显低于治疗前(P<0.05).结论 对MODS患者采用连续性血液净化治疗具有良好的临床疗效,可有效改善患者的生存质量,且安全性较高,值得临床上推广应用.

关 键 词:连续性血液净化  多脏器功能障碍综合征  血流动力学  临床疗效

Treatment Application Of Continuous Blood Purification Therapy In Multiple Organ Dysfunction Syndrome
Abstract:Objective To study the Observation and analysis of multiple organ dysfunction syndrome (MODS) patients with clinical effect of continuous blood purification therapy designed to provide an effective basis for clinical treatment.Methods The group collected set in March 2010 and March 2015 in our hospital ICU admissions 40 patients with MODS clinical studies, were given continuous blood purification treatment, hemodynamic and recorded before and after treatment.Results After the therapy the CV and HR index was significantly lower than before treatment (P <0.05), MAP, CI parameters were significantly higher than before treatment (P <0.05);Hcy and ET-1 indexes significantly lower than before treatment.Conclusions To MODS patients with continuous blood purification therapy has good clinical efficacy, which can effectively improve the quality of life of patients, and high security, it should be widely applied clinically.
Keywords:CRRT  MODS  Hemodynamics  Clinical efficacy
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