| Abstract: | The occurrence of osteosarcoma is related to a variety of oncogenes and tumor suppressor genes. DNA methylation is an important feature of epigenetics, which can cause the activation of oncogenes and the inactivation of tumor suppressor genes. DNA methylation is an important factor in the study of metastasis, recurrence and drug resistance of osteosarcoma. To study the methylation of osteosarcoma-related genes provides theoretical support for the study of the occurrence, metastasis and drug resistance of osteosarcoma, and provides a theoretical basis for clinical diagnosis, prognosis prediction, targeted therapy and the study of new drugs. |
