| 三黄汤对肥胖2型糖尿病胰岛素抵抗和炎症因子的影响 |
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| 引用本文： | 叶丽芳,王旭,尚文斌,张舒,高燕.三黄汤对肥胖2型糖尿病胰岛素抵抗和炎症因子的影响[J].中国实验方剂学杂志,2013,19(7):289-292. |
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| 作者姓名： | 叶丽芳 王旭 尚文斌 张舒 高燕 |
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| 作者单位： | 南京中医药大学附属医院,南京 210029;南京中医药大学,南京 210046;南京中医药大学,南京 210046;南京中医药大学,南京 210046;南京中医药大学附属医院,南京 210029;南京中医药大学,南京 210046 |
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| 基金项目： | 国家自然科学基金项目(项目编号：81073110),江苏省普通高校研究生科技创新计划(项目编号：2010CXJH464)江苏高校优势学科建设工程(中西医结合)项目(项目编号：20110625) |
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| 摘 要： | 目的: 观察三黄汤对肥胖2型糖尿病胰岛素抵抗指标和炎症因子的影响。 方法: 将符合西医诊断2型糖尿病,又符合中医"痰湿热结证"患者共69例,随机分为加用中药组和单用西药组,进行了3个月的疗效观察。对治疗前后临床症状、糖脂代谢指标、胰岛素抵抗指标及炎症因子等进行比较分析。 结果: 加用中药三黄汤组(黄连3 g,黄芩10 g,制大黄6 g),在改善患者临床症状、糖脂代谢指标(空腹血糖、餐后2 h血糖、糖化血红蛋白、甘油三酯,P<0.05)、胰岛素抵抗指标(HOMA-胰岛素抵抗指数,P<0.05)方面优于单用西药组,并对炎症因子 有一定降低作用。 结论: 加用三黄汤组临床疗效优于单用西药组。
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| 关 键 词： | 三黄汤 肥胖 2型糖尿病 胰岛素抵抗 炎症因子 |
| 收稿时间： | 2012/10/15 0:00:00 |
Effect of Sanhuang Tang on Insulin Resistance Index and Inflammatory Factors of Obese Type-2 Diabetes |
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| YE Li-fang,WANG Xu,SHANG Wen-bin,ZHANG Shu and GAO Yan.Effect of Sanhuang Tang on Insulin Resistance Index and Inflammatory Factors of Obese Type-2 Diabetes[J].China Journal of Experimental Traditional Medical Formulae,2013,19(7):289-292. |
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| Authors: | YE Li-fang WANG Xu SHANG Wen-bin ZHANG Shu and GAO Yan |
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| Institution: | Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing 210029, China;Nanjing University of Chinese Medicine, Nanjing 210046, China;Nanjing University of Chinese Medicine, Nanjing 210046, China;Nanjing University of Chinese Medicine, Nanjing 210046, China;Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing 210029, China;Nanjing University of Chinese Medicine, Nanjing 210046, China |
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| Abstract: | Objective: To observe the efficacy of Chinese herbal formula Sanhuang tang in treating obese type-2 diabetes. Method: Sixty-nine patients conformed to western medicine diagnosis of type 2 diabetes and traditional Chinese medicine's phlegm hot junction card were randomly distributed into Sanhuang tang group and western medicine group.After treatment for 3 months, comparative analysis of glucose and lipid metabolism indicators, indicators of insulin resistance and inflammatory factors. Result: Herbal superior in improving clinical symptoms, glucose and lipid metabolism and insulin resistance index with western medicine group, and reduce the lever of inflammatory factors to some extent. Conclusion: Both western and herbal formula treatment has better efficacy. |
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| Keywords: | Sanhuang Tang obesity type 2 diabetes insulin resistance inflammatory factors |
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