Regression of gastric T cell lymphoma with eradication of Helicobacter pylori |
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Authors: | Bariol C Field A Vickers C R Ward R |
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Affiliation: | Department of Gastroenterology, St Vincent's Hospital, Sydney, Australia. bariol@ozemail.com.au |
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Abstract: | Helicobacter pylori is thought to be important in the pathogenesis of chronic active gastritis, peptic ulceration, gastric adenocarcinoma, and gastric B cell lymphoma of mucosa associated lymphoid tissue. The mechanism of evolution from chronic gastritis to monoclonal B cell proliferation is not known but is thought to be dependent on antigen specific T cells to H pylori and its products. Here, we report a case of gastric T cell lymphoma associated with chronic H pylori gastritis which regressed with eradication of the organism. This is the first report of a gastric T cell lymphoma regressing with H pylori eradication, and suggests a causal link between primary gastric T cell lymphoma and this organism. |
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Keywords: | Helicobacter pylori T cell lymphoma |
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