Effect of Autochthonous Serum on Lymphocyte Response to Tumor Cells and Phytohemagglutinin in Patients With Various Types of Cancer |
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Authors: | KUROSU, YASUHIKO SAEGUSA, YOSHIBUMI HIRONAKA, TARO MORITA, KEN |
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Affiliation: | First Department of Surgery, Nihon University School of Medicine Tokyo |
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Abstract: | The serum-blocking effect on lymphocyte response to both authochthonoustumor cells and phytohemagglutinin (PHA) in sera of patientswith various types of cancer was evaluated. The blocking effecton lymphocyte respone to tumor cells correlated with the tumorburden and the subsequent clinical course of the disease. Theeffect on response to PHA, however, showed no significant relationshipwith either the tumor burden or the subsequent clinical course.Under the experimental conditions, no significant correlationof the serum-blocking effect on lymphocyte response to tumorcells with that on lymphocyte response to PHA was found. |
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