肤乐霜治疗婴幼儿湿疹和特应性皮炎的临床观察

目的：探讨肤乐霜治疗婴幼儿湿疹和特应性皮炎的效果有效性，并观察其安全性。方法：选取什么医院什么时间段婴幼儿湿疹和特应性皮炎患儿71例，给予肤乐霜均匀涂于患处，2次/d。在治疗前后分别对红斑、水肿/浸润/丘疹、抓痕、渗出/结痂、鳞屑/干皮征、苔藓样变的积分进行评价并记录不良事件。结果：肤乐霜治疗湿疹和特应性皮炎的总显效率为62%，其中急性湿疹为68.2%，亚急性湿疹为62.5%，慢性湿疹为53.3%，特应性皮炎为61.1%。婴幼儿湿疹和特应性皮炎总显效率差异无统计学意义；治疗后的SCORDA评分均较治疗前有显著降低（P<0.01）；不良反应均为一过性，未影响治疗。结论：肤乐霜对婴幼儿湿疹和特应性皮炎均有良好疗效，安全性高，值得临床推广应用。

Fule Cream in the Treatment of Infantile Eczema and Atopic Dermatitis in Clinical Observation

Objective: To evaluate the efficacy and safety of fule cream for the theatment of infantile eczema and atopic dermatitis. Method: Fule cream was used twice a day in 71 children with eczema and atopic dermatitis. These symptom scores of erythema, edema/infiltration/papules, scratches, oozing/crusting, scaling/dry skin syndrome and lichenification were compared before and after the treatment. At the same time, the adverse events were recorded. Result: The total effective rate of the treatment in infantile eczema and atopic dermatitis was 62%. The effective rate in the children with acute eczema, subacute eczema, chronic eczema and atopic dermatitis were 68.2%, 62.5%, 53.3% and 61.1%, respectively. The difference for total effective rate among the four groups was not significant among three groups.SCORDA scores after the treatment were significantly lower than that before the treatment (P<0.01). Adverse reactions were transient, which had no impacts on the treatment. Conclusion: Fule cream have a promising efficacy for the treatment of infantile eczema and atopic dermatitis with a high safety.