Oncogenic osteomalacia of the cervical spine: a rare case of curative resection and reconstruction |
| |
Authors: | Akhter Murtaza Sugrue Patrick A Bains Rick Khavkin Yevgeniy A |
| |
Institution: | Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, 675 North St. Clair Street, Chicago, Illinois 60611, USA. |
| |
Abstract: | Oncogenic osteomalacia (OO) is a rare paraneoplastic syndrome, with only 100 reported cases in the literature. The majority of OO-associated mesenchymal tumors are due to a lesion called phosphaturic mesenchymal tumor, mixed connective tissue (PMTMCT) variant. There have been only 6 reported cases of OO of the spine. With this paper the authors present a case of OO of the cervical spine in a patient who initially presented with multiple pathological fractures of unknown cause, and who eventually underwent staged C-5 spondylectomy followed by circumferential stabilization. Resection of the cervical lesion led to resolution of his hypophosphatemia and prevention of any further pathological fractures. The authors describe a rare cervical neoplasm, its treatment, and review the literature on this rare bony pathological entity. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|