In vitro synergy studies with Clostridium difficile. |
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| Authors: | A E Bacon S McGrath R Fekety W J Holloway |
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| Affiliation: | Department of Medicine, Medical Center of Delaware, Wilmington 19899. |
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| Abstract: | Agar dilution anaerobic susceptibility studies using rifampin, vancomycin, metronidazole, and bacitracin individually and in combination were performed with Clostridium difficile. Fifty-five strains of C. difficile were studied. Eighty-five percent of strains tested (29 of 34) were synergistically inhibited by the combination of bacitracin and rifampin (fractional inhibitory concentration, less than or equal to 0.50). |
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