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Synthesis and antiviral assays of some benzimidazole nucleosides and acyclonucleosides.
Authors:L Garuti  M Roberti  G Gentilomi
Affiliation:Department of Pharmaceutical Science, University of Bologna, Italy. lauga@alma.unibo.it
Abstract:Some benzimidazole nucleosides and acyclonucleosides were synthesized and tested in vitro as antiviral agents. None of them showed significant activity. Replacement of the benzenesulphonyl group at N-1 with the ribofuranosyl moiety or with the acyclovir side-chain was deleterious.
Keywords:
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