Synthesis and antiviral assays of some benzimidazole nucleosides and acyclonucleosides. |
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Authors: | L Garuti M Roberti G Gentilomi |
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Affiliation: | Department of Pharmaceutical Science, University of Bologna, Italy. lauga@alma.unibo.it |
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Abstract: | Some benzimidazole nucleosides and acyclonucleosides were synthesized and tested in vitro as antiviral agents. None of them showed significant activity. Replacement of the benzenesulphonyl group at N-1 with the ribofuranosyl moiety or with the acyclovir side-chain was deleterious. |
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