| 放射性核素骨显像联合血清CA15-3、CA50、IL-8评价乳腺癌骨转移的临床意义 |
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| 引用本文： | 蒋炳辰,张雪辉,高永旺,陈方旎,肖国有,姚少红.放射性核素骨显像联合血清CA15-3、CA50、IL-8评价乳腺癌骨转移的临床意义[J].右江医学,2013(2):189-191. |
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| 作者姓名： | 蒋炳辰 张雪辉 高永旺 陈方旎 肖国有 姚少红 |
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| 作者单位： | 广西北海市人民医院核医学科;广西医科大学研究生院;广西医科大学附属肿瘤医院核医学科 |
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| 摘 要： | 目的评价血清CA15-3、CA50、IL-8联合放射性核素骨显像对乳腺癌患者骨转移诊断的临床意义。方法利用SPECT/CT对乳腺癌患者进行骨骼放射性核素骨显像,应用化学发光法和放射免疫法对84例乳腺癌患者(均为女性)进行血清CA15-3、CA50、IL-8含量检测,并与34名正常人(均为女性)进行相关对比分析。结果乳腺癌患者骨转移的血清CA15-3、CA50、IL-8含量水平明显高于正常人组(P<0.01),乳腺癌骨转移组灶数>2个的肿瘤标志物水平明显高于灶数≤2个的肿瘤标志物水平(P<0.01)。结论在进行放射性SPECT/CT显像同时,进行血清CA15-3、CA50和IL-8的检测,能够尽早发现乳腺癌骨转移。
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| 关 键 词： | 乳腺癌 SPECT/CT A15-3 CA50 IL-8 |
Assessment of bone metastasis of breast cancer by radionuclide bone scan combined with CA15-3,CA50 and IL-8 on |
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| JIANG Bingchen,ZHANG Xuehui,GAO Yongwang,Chen Fangyi,XIAO Guoyou,YAO Shaohong.Assessment of bone metastasis of breast cancer by radionuclide bone scan combined with CA15-3,CA50 and IL-8 on[J].Youjiang Medical Journal,2013(2):189-191. |
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| Authors: | JIANG Bingchen ZHANG Xuehui GAO Yongwang Chen Fangyi XIAO Guoyou YAO Shaohong |
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| Institution: | 1(1.Department of Nuclear Medicine,Beihai People’s Hospital,Beihai;2.The Graduate School of Guangxi Medical University,Nanning 530021,Guangxi,China;3.Department of Nuclear Medicine,the Affiliated Tumor Hospital of Guangxi Medical University,Nanning 530021,China) |
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| Abstract: | Objective To assess the value of radionuclide bone scan combined with serum CA15-3,CA50,IL8 in the diagnosis of bone metastasis of breast cancer.Methods Patients with breast cancer were tested by SPECT/CT for bone scanning,and serum CA15-3,CA50,IL-8 of 84 breast cancer patients(females) were detected by RIA and CLIA.Then,all relative data of the breast cancer patients were compared with those of 34 healthy people(females).Results The serum CA15-3,CA50,IL-8 levels in breast cancer patients with bone metastasis were significantly higher than those in the healthy people(P<0.01).Among all the breast cancer patients,the tumor marker levels in patients with more than 2 bone lesions were significantly higher than those in patients with 2 or less than 2 bone lesions(P<0.01).Conclusion Testing serum CA15-3,CA50,IL-8 levels while taking SPECT/CT can help discover bone metastasis breast cancer early. |
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| Keywords: | breast cancer SPECT/CT CA15-3 CA50 IL-8 |
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