| 海南狗牙花化学成分的研究 |
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| 引用本文： | 黄建鹏,马养民,姜建双,张培成.海南狗牙花化学成分的研究[J].中国中药杂志,2006,31(14):1166-1168. |
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| 作者姓名： | 黄建鹏 马养民 姜建双 张培成 |
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| 作者单位： | 1. 西北农林科技大学,生命科学学院,陕西,杨凌,712100
2. 中国协和医科大学,中国医学科学院药物研究所,北京,100050 |
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| 摘 要： | 目的：对夹竹桃科植物海南狗牙花Ervatamia hainanensis中化学成分进行系统研究。方法：用硅胶柱色谱法和光谱分析法分离和鉴定化学成分。结果：从海南狗牙花中分离到8个化合物：α-amyrin acetate(1),11-oxo-α-amyrin acetate(2),β-谷甾醇(β-sitosteol,3),cycloart-23-ene-3β,25-diol(4),cycloart-25-ene-3β,24-diol(5),5α,8α-epidioxyergosta-6,22-dien-3β-ol(6),ibogamin-3-one(7),β-胡萝卜苷(β-daucosterol,8)。结论：化合物1,2,4～7为首次从该植物中获得。
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| 关 键 词： | 海南狗牙花 三萜 生物碱 甾体 |
| 文章编号： | 1001-5302（2006）14-1166-03 |
| 收稿时间： | 2006-02-15 |
| 修稿时间： | 2006-02-15 |
Studies on constituents from root and stem of Ervatamia hainanensis |
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| HUANG Jian-peng ;MA Yang-min ;JIANG Jian-shuang ;ZHANG Pei-cheng.Studies on constituents from root and stem of Ervatamia hainanensis[J].China Journal of Chinese Materia Medica,2006,31(14):1166-1168. |
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| Authors: | HUANG Jian-peng ;MA Yang-min ;JIANG Jian-shuang ;ZHANG Pei-cheng |
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| Institution: | 1. College of Life Science Northvest Agriclture and Forestry Uniaersity, Yangling 712100, China; Institute of Materia Medica, Chinese Academy of Medical Science, Peking Union Medical College, Beijing 100050,China |
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| Abstract: | OBJECTIVE: To investigate the constituents of Ervatamia hainanensis systematically. METHOD: Various chromatographic techniques were applied to isolate and purify the constituents of this plant. The structures were elucidated by spectroscopic analysis. RESULT: Eight compounds were obtained, which were identified as alpha-amyrin acetate (1), 11-oxo-alpha-amyrin acetate (2), beta-sitosterol (3), cycloart-23-ene-3beta, 25-diol(4), cycloart-25-ene-3beta, 24-diol (5), 5alpha, 8alpha-epidioxyergosta-6, 22-dien-3beta-ol (6), ibogamin-3-one (7), beta-daucosterol (8). CONCLUSION: Compounds 1, 2, 4- 7 were isolated from this plant for the first time. |
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| Keywords: | Ervatamia hainanensis triterpenoid alkaloids steroids |
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