Effect of glycerol on cerebral blood flow in chronic cerebral ischemic disease |
| |
Authors: | Hirofumi Oyama MD Masahiro Niwa Yoshihisa Kida MD Takayuki Tanaka MD Takanori Iwakoshi Ryuji Kitamura Satoshi Maezawa Tatsuya Kobayashi MD |
| |
Institution: | Department of Neurosurgery, Komaki City Hospital, 1-20 Jobushi, Komaki city, Aichi, 485 Japan |
| |
Abstract: | The change of cerebral blood flow (CBF) after glycerol infusion was analyzed in 10 cases of lacunar infarction and 11 cases of ischemic disease of major artery: 6 cases of internal carotid artery occlusion and 5 cases of middle cerebral artery occlusion. In lacunar infarction, CBF increased generally except for the corona radiata and the increased ratio was about 20%. In cases with ischemic disease of a major artery, the CBF tended to increase in the non-affected hemisphere after glycerol infusion. But CBF did not always increase in the affected hemisphere; rather it decreased in the temporal and parietal lobes and especially in the corona radiata. The blood flow of the affected hemisphere might be stealed to the non-affected hemisphere after glycerol infusion. This phenomenon might be caused by a poor cerebrovascular reserve capacity of the maximally dilated vessels in the affected side. |
| |
Keywords: | glycerol CBF cerebral ischemia |
本文献已被 ScienceDirect 等数据库收录! |