| 苦石莲化学成分的分离与鉴定（IV） |
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| 引用本文： | 张晓书； 韩瑞亭；高慧媛； 李卫东；吴兆华. 苦石莲化学成分的分离与鉴定（IV）[J]. 沈阳药科大学学报, 2012, 29(2): 98-103 |
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| 作者姓名： | 张晓书； 韩瑞亭；高慧媛； 李卫东；吴兆华 |
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| 作者单位： | (1. 沈阳药科大学,教育部基于靶点的药物设计与研究重点实验室,辽宁 沈阳 110016;2. 黑龙江农业经济职业学院 制药工程系,黑龙江 牡丹江 157041;3. 牡丹江医学院 药学系,黑龙江 牡丹江 157011) |
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| 基金项目： | 黑龙江省自然科学基金资助项目(D200947);黑龙江省中医药管理局资助项目(10W72);辽宁省高等学校优秀人才支持计划资助项目(LJQ2011103) |
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| 摘 要： | 目的对苦石莲中的化学成分做进一步研究。方法采用硅胶柱色谱、凝胶柱色谱和重结晶等多种方法分离纯化,根据理化性质及波谱学数据进行结构鉴定。结果分离得到9个化合物,分别鉴定为全反式-5-脱氧戊糖酸-γ-内酯(all-trans-5-deoxy-pentonic acid-γ-lactone,1)、腺苷(adeno-sine,2)、胡萝卜苷-6’-O-硬脂酸酯(daucosterol-6’-O-stearate,3)、7-acetoxybonducellpin C(4)、caesal-pinin K(5)、norcaesalpinin E(6)、neocaesalpin A(7)、neocaesalpin L(8)、neocaesalpin M(9)。结论化合物1、2为首次从云实属植物中分离得到,化合物3～5、7为首次从喙荚云实植物中分离得到。
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| 关 键 词： | 喙荚云实 苦石莲, 化学成分, 结构鉴定, |
| 收稿时间： | 2011-07-01 |
| 修稿时间： | 2012-01-05 |
Chemical constituents from the seeds of Caesalpinia minax Hance (IV) |
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| ZHANG Xiao-shu,HAN Rui-ting,GAO Hui-yuan,LI Wei-dong,WU Zhao-hua. Chemical constituents from the seeds of Caesalpinia minax Hance (IV)[J]. Journal of Shenyang Pharmaceutical University, 2012, 29(2): 98-103 |
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| Authors: | ZHANG Xiao-shu HAN Rui-ting GAO Hui-yuan LI Wei-dong WU Zhao-hua |
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| Affiliation: | 1.Key Laboratory of Structure-Based Drug Design & Discovery,Ministry of Education,Shenyang Pharmaceutical University,Shenyang 110016,China;2.Department of Pharmaceutical Engineering,Heilonjiang Agricultural Economy Vocational College,Mudanjiang 157041,China;3.Department of Pharmacology,Mudanjiang Medical College,Mudanjiang 157011,China) |
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| Abstract: | Objective To study the chemical constituents from the seeds of Caesalpinia minax Hance.Methods Compounds were isolated by column chromatography on silica gel,Sephadex LH-20 together with recrystallization methods and identified by their physical-chemical properties and spectral analysis.Results Nine compounds were obtained and elucidated as:all-trans-5-deoxy-pentonic acid-γ-lactone(1),adenosine(2),daucosterol-6′-O-stearate(3),7-acetoxybonducellpin C(4),caesalpinin K(5),norcaesalpinin E(6),neocaesalpin A(7),neocaesalpin L(8)and neocaesalpin M(9),respectively.Conclusions Compounds 1 and 2 are isolated from Caesalpinia genus for the first time,compounds 3,4,5 and 7 are isolated from this plant for the first time. |
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| Keywords: | Caesalpinia minax Hance')" >Caesalpinia minax Hance Kushilian chemical constituent structure identification |
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