沙生蜡菊花降脂活性部位化学成分的分离与鉴定(Ⅱ)

目的沙生蜡菊花降脂活性部位中的化学成分研究。方法采用硅胶、ODS、制备HPLC等多种色谱方法分离纯化,依据理化性质、波谱数据分析进行结构鉴定。结果从沙生蜡菊花的降脂活性部位中分离得到11个化合物,并分别鉴定为:丁香苷(syringin,1)、二氢丁香苷(dihydrosyringin,2)、(E)-4-hydroxybenzalacetone-3-O-β-D-glucopyranoside(3)、4-烯丙基-2-甲氧基苯基1-O-β-D-呋喃芹糖(1-6)-β-D-吡喃葡萄糖苷4-allyl-2-methoxyphenyl 1-O-β-D-apiofuranosyl-(1-6)-O-β-D-glu-copyranoside,4]、苔黑酚-β-D-吡喃葡萄糖苷(orcinol-β-D-glucopyranoside,5)、7-hydroxy-5-me-thoxyphthalide-7-O-β-D-glucopyranoside(6)、5,7-dihydroxyphthalide-7-O-β-D-glucopyranoside(7)、undulatoside A(8)、adenosine(9)、maltol-3-O-β-D-apiofuranosyl-(1-6)-β-D-glucopyranoside(10)、2,4,6-三羟基苯乙酮-2,4-二-O-β-D-吡喃葡萄糖苷(2,4,6-trihydroxylacetophenone-2,4-di-O-β-D-glu-copyranoside,11)。结论化合物1～11均为首次从蜡菊属植物中分离得到。

Isolation and identification of chemical constituents in the lipid-lowering fraction of Flos Helichrysum arenarium II

Objective To study the chemical constituents in the lipid-lowering fraction of Flos Helichrysum arenarium.Methods The chemical constituents were isolated by various methods of isolation(silica gel,ODS and HPLC column chromatography)and their structures were elucidated by the analysis of spectral data and chemical properties.Results Eleven compounds were identified as syringin(1),dihydrosyringin(2),(E)-4-hydroxybenzalacetone-3-O-β-D-glucopyranoside(3),4-allyl-2-methoxyphenyl-1-O-β-D-apiofuranosyl-(1-6)-O-β-D-glucopyranoside(4),orcinol-β-D-glucopyranoside(5),7-hydroxy-5-methoxyphthalide-7-O-β-D-glucopyranoside(6),5,7-dihydroxyphthalide-7-O-β-D-glucopyranoside(7),undulatoside A(8),adenosine(9),maltol-3-O-β-D-apiofuranosyl-(1-6)-β-D-glucopyranoside(10),and 2,4,6-trihydroxylacetophenone-2,4-di-O-β-D-glucopyranoside(11).Conclusions Compounds 1-11 are obtained from Helichrysum for the first time.