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Adrenergic Stimulation Mediates Visceral Hypersensitivity to Colorectal Distension Following Heterotypic Chronic Stress
Authors:John H. Winston  Sushil K. Sarna
Affiliation:? Enteric Neuromuscular Disorders and Visceral Pain Center, Department of Internal Medicine, Division of Gastroenterology, The University of Texas, Medical Branch at Galveston, Galveston, Texas
Enteric Neuromuscular Disorders and Visceral Pain Center, Department of Neuroscience and Cell Biology, Division of Gastroenterology, The University of Texas, Medical Branch at Galveston, Galveston, Texas
Abstract:
Keywords:CRD, colorectal distention   CRH, corticotrophin-releasing hormone   DiI, 1,1&prime  -dilinoleyl-3,3,3&prime  ,3&prime  -tetramethylindocarbocynine perchlorate   DRG, dorsal root ganglia   HeCS, heterotypic chronic stress   HPA, hypothalamus-pituitary-adrenal axis   IBS, irritable bowel syndrome   MPO, myeloperoxidase   NGF, nerve growth factor   trkA, tropomyosin-related kinase A (NGF high-affinity receptor)
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