C反应蛋白检测用于儿科疾病诊治的价值

目的探讨CRP在儿科疾病诊治中的意义。方法测定住院患儿住院期间最高CRP疽及白细胞总数，按高低分为六组，比较感染性疾病中每组血白细胞总数、CRP与血浆钙素原（PCT）的关系，及治疗前后血白细胞总数和CRP变化情况。结果CRP与PCT呈正相关（P〈0．01），而白细胞计数大部分与PCT没有相关性。六组中有三组白细胞总数治疗前后变化无统计学意义，而CRP异常的第5组治疗前后差异有统计学意义（P〈0．05）。结论CRP不仅可作为儿童细菌感染和病毒感染的初步鉴别指标，还可反映炎症的严重程度。CRP应作为门诊发热患者的一项常规检查，联合血象一起分析对减少抗生素的滥用有很大的作用。

The value of detection of C-reactive protein for the diagnosis and treatment of pediatric diseases

Objective To explore the significance of CRP in the diagnosis and treatment of pediatric diseases. Methods The highest CRP value and the total number of white blood cells of hospitalized children during hospitalization were detected ,divided into 6 groups according to the level. To compare the relationship among the total number of WBC,CRP and PCT of each group in the infectious diseases and compare the changes of the total number of WBC and CRP before and after treatment. Results CRP and serum procalcitonin (PCT) was positively correlated (P ＜ 0.01), but a large part of white blood cells did not associate with the PCT. In total white blood cells of 6 groups,3 groups had no statistically significant changes before and after treatment, while the CRP abnormal changes of 5 groups before and after treatment was statistically significant(P ＜0.05). Conclusion CRP was not only as the initial identification of indicators of the children with bacterial infections and viral infections,but also reflected the severity of inflammation. CRP should be used as a routine examination of outpatient with fever, associated with the analysis of the white blood cell could play an important role in reducing the abuse of antibiotics.