止嗽散加减治疗小儿咳嗽变异性哮喘的临床研究

目的观察止嗽散对小儿咳嗽变异性哮喘的疗效。方法将110例咳嗽变异性哮喘患儿随机分为治疗组和对照组各55例，对照组给予口服沙丁胺醇、酮替芬、二氯苯那敏等；治疗组在对照组治疗方案的基础上给予止嗽散加减治疗。两周后比较两组的临床疗效。结果治疗组的总有效率为90．9％，优于对照组的总有效率（76．4％）（χ^2=4．25，P〈0．05）；6个月后咳嗽对照组复发率为60．0％，治疗组16．3％，两组差异有统计学意义（χ^2=22．18，P〈0．01）。结论常规治疗联合止嗽散加减能够明显的提高咳嗽变异性哮喘的疗效。

Clinical study of Zhisousan in treatment of children with cough variance asthma

Objective To study the curative effect of Zhisousan in treatment of children with cough variance asthma. Methods 110 cough variance asthma children were randomly divided into treatment group and control group,each group 55 patients.The control group received western medicine's ordinary treatment,and the treatment group were given Zhisousan except received western medicine.Then the therapeutic effect were compared between the two groups after two weeks treatment. Results The treatment group's total effective rate 90.9% was obviously higher than the control group 76.4%,and there was significant statistical difference(x2 = 4.25,P＜0.05);The trentment group's cough recurrence rate was 16.3%,and the control group was 60.0%,and there was significant statistical difference(x2 = 22.18,P＜0.01). Conclusion The therapeutical method of Zhisousan combined with western medicine could obviously raise the therapeutic effect.