| 山药多糖对糖尿病小鼠降血糖作用的研究 |
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| 引用本文： | 丁岩平. 山药多糖对糖尿病小鼠降血糖作用的研究[J]. 中国基层医药, 2011, 18(5): 604-605. DOI: 10.3760/cma.j.issn.1008-6706.2011.05.013 |
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| 作者姓名： | 丁岩平 |
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| 作者单位： | 中国重型汽车集团有限公司医院药剂科,山东省济南,250031 |
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| 摘 要： | 目的 探讨山药多糖对糖尿病小鼠的降血糖作用.方法 将90只小鼠随机分成山药多糖组、 格列苯脲组和健康对照组,各30只.小鼠经腹腔注射200 mg/kg四氧嘧啶建立糖尿病小鼠模型,用山药多糖？ 连续给小鼠模型灌胃给药12 d,以格列苯脲作阳性对照.结果 山药多糖组对糖尿病小鼠的血糖有明显降低 作用,与格列苯脲组比较差异无统计学意义（P＞0.05）.结论 山药多糖具有显著的降血糖作用.
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| 关 键 词： | 山药多糖 糖尿病小鼠 降血糖 |
Experimental study on the effect of yam polysaccharide for diabetic mice |
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| DING Yan-ping. Experimental study on the effect of yam polysaccharide for diabetic mice[J]. Chinese Journal of Primary Medicine and Pharmacy, 2011, 18(5): 604-605. DOI: 10.3760/cma.j.issn.1008-6706.2011.05.013 |
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| Authors: | DING Yan-ping |
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| Affiliation: | DING Yan-ping( 1.Department of Phar macy,The Hospital of China Heavy Duty Truck Group Co ,Ltd ,Jinan, Shandong 250031,China;) |
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| Abstract: | Objective To explore the effect of yam polysaccharide for the diabetic mice. Methods Ninty mice were randomly divided into three groups ,yam polysaccharide group(n = 30), glibenclamide group (n = 30) and control group(n = 30). Mice were Intraperitoneal injection of alloxan (200mg/kg) to establish diabetic model. Yam polysaccharide group was administered yam polysaccharide for 12d. Results Yam polysaccharide significantly decreased the blood sugar of the diabetic mice. There were not significantly different in two groups (P ＞ 0.05).Conclusion Yam polysaccharide had obvious role in decreasing blood glucose. |
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| Keywords: | Yam polysaccharide Diabetes mellitus mice Decreasing blood sugar |
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