| 血清γ干扰素诱导蛋白-10、IL-8在初诊DM2中的表达及意义 |
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| 引用本文： | 冯真贵 杨士军. 血清γ干扰素诱导蛋白-10、IL-8在初诊DM2中的表达及意义[J]. 放射免疫学杂志, 2005, 18(6): 462-463 |
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| 作者姓名： | 冯真贵 杨士军 |
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| 作者单位： | 南京医科大学附属淮安市第一人民医院,223300 |
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| 摘 要： | 目的：探讨炎症细胞因子γ干扰素诱导蛋白-10（IP-10）、白介素-8（IL-8）在2型糖尿病（DM2）患者中的表达及意义。方法：检测37例初诊DM2患者及健康人33例血清IP-10、IL-8浓度并予对照分析。结果：DM2组IP-10、IL-8浓度均显著高于健康人。结论：IP-10、IL-8在DM2发病中可能起一定作用。
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| 关 键 词： | γ干扰素诱导蛋白-10 白介素-8 2型糖尿病 基因表达 |
| 收稿时间： | 2005-09-23 |
| 修稿时间： | 2005-10-12 |
The Expression and Significance of Serum IP- 10 and IL- 8 in Patients with Recently Diagnosed Type 2 Diabetes Mellitus |
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| Feng Zhengui, Yang Shijun. The Expression and Significance of Serum IP- 10 and IL- 8 in Patients with Recently Diagnosed Type 2 Diabetes Mellitus[J]. Journal of Radioimmanology, 2005, 18(6): 462-463 |
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| Authors: | Feng Zhengui Yang Shijun |
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| Abstract: | Objective To investigate the significance of IL-10 and IL-8 in the pathogenesis of type2 diabetes mellitus(DM2).Methods The serum levels of IL-10 and IL-8 were measured in 37 patients with recently diagnosed type 2 diabetes mellitus and 33 controls.Results The serum levels of IL-10 and IL-8 patients with DM2 were significantly higher than those in controls(P<0.001).Conclusion The higher levels of IL-10 and IL-8 might play some role in the pathogenesis of DM2. |
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| Keywords: | IL- 10 IL-8 DM2 |
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