| Study of the effects of mild hypothermia on cerebral PO2, PCO2 and pH and body temperature in patients with acute severe head injury |
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| 引用本文： | 贾军 林源泉 刘文峰 钟天安 张浚 叶宇 许亦群. Study of the effects of mild hypothermia on cerebral PO2, PCO2 and pH and body temperature in patients with acute severe head injury[J]. 中华创伤杂志(英文版), 2005, 8(3): 138-141 |
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| 作者姓名： | 贾军 林源泉 刘文峰 钟天安 张浚 叶宇 许亦群 |
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| 作者单位： | Department of Neurosurgery，Shenzhen Longgang Central Hospital，Shenzhen 518116，China，Department of Neurosurgery，Shenzhen Longgang Central Hospital，Shenzhen 518116，China，Department of Neurosurgery，Shenzhen Longgang Central Hospital，Shenzhen 518116，China，Department of Neurosurgery，Shenzhen Longgang Central Hospital，Shenzhen 518116，China，Department of Neurosurgery，Shenzhen Longgang Central Hospital，Shenzhen 518116，China，Department of Neurosurgery，Shenzhen Longgang Central Hospital，Shenzhen 518116，China，Department of Neurosurgery，Shenzhen Longgang Central Hospital，Shenzhen 518116，China |
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| 基金项目： | ItemofscienceandtechnologyprojectofShenzhencity, Guangdongprovince(Serialnumber:thescienceandtechnology bureauofShenzhencity[2004]164 200405070) |
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| 摘 要： | I nrecent20yearsmostanimalexperimentsandclinicalstudieshavedemonstratedthatmildhypothermia(32℃ 35℃)hasaffirmatoryeffectonbrainprotection.Butthereareafewresearchreportsthatdenythebrainprotectioneffectofmildhypothermia.Wetreated38patientswithacuteseverehe…
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| 关 键 词： | 体温 急性脑损伤 pH值 二氧化碳 PO2 PCO2 |
Study of the effects of mild hypothermia on cerebral PO2, PCO2 and pH and body temperature in patients with acute severe head injury |
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| JIA Jun,LIN Yuan-quan,LIU Wen-feng,ZHONG Tian-an,ZHANG Jun,YE Yu,XU Yi-qun. Study of the effects of mild hypothermia on cerebral PO2, PCO2 and pH and body temperature in patients with acute severe head injury[J]. Chinese journal of traumatology, 2005, 8(3): 138-141 |
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| Authors: | JIA Jun LIN Yuan-quan LIU Wen-feng ZHONG Tian-an ZHANG Jun YE Yu XU Yi-qun |
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| Affiliation: | Department of Neurosurgery, Shenzhen Longgang Central Hospital, Shenzhen 518116, China |
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| Abstract: | OBJECTIVE: To study the effects of mild hypothermia on cerebral oxygen partial pressure, carbon dioxide partial pressure, pH and body temperature (PbrO2, PbrCO2, pHbr and BT) in patients with acute severe head injury. METHODS: Thirty-eight patients with acute severe head injury were treated with mild hypothermia, meantime PbrO2, PbrCO2, pHbr and BT were monitored in order to study the changes of PbrO2, PbrCO2, pHbr and BT. RESULTS: In patients with acute head injury, mild hypothermia obviously increased PbrO2, decreased PbrCO2 and CO2 accumulation and acidosis in brain tissue. BT was 1-1.5 deg. higher than rectal temperature (RT) after injury. The BT and RT were decreased when the patients were treated with mild hypothermia, but at the same time the difference between BT and RT was increased. CONCLUSIONS: In patients with acute severe head injury the direct monitoring of PbrO2, PbrCO2, pHbr and BT was safe and reliable, and is helpful in estimating prognosis and mild hypothermia therapy. |
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| Keywords: | Head Wounds and injuries Mild hypothermia |
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