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Evidence to Support Monitoring of Vedolizumab Trough Concentrations in Patients With Inflammatory Bowel Diseases |
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| Authors: | Erwin Dreesen Bram Verstockt Sumin Bian Magali de Bruyn Griet Compernolle Sophie Tops Maja Noman Gert Van Assche Marc Ferrante Ann Gils Séverine Vermeire |
| Affiliation: | 1. Laboratory for Therapeutic and Diagnostic Antibodies, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven – University of Leuven, Leuven, Belgium;3. Translational Research in GastroIntestinal Disorders, Department of Clinical and Experimental Medicine, KU Leuven – University of Leuven, Leuven, Belgium;4. Department of Gastroenterology and Hepatology, University Hospitals Leuven, KU Leuven – University of Leuven, Leuven, Belgium |
| Abstract: | |
| Keywords: | Monoclonal Antibody Integrin Pharmacokinetics Therapeutic Drug Monitoring ADA antidrug antibody AUROC area under the receiver operating characteristic curve CD Crohn’s disease CRP C-reactive protein MAdCAM-1 mucosal addressin cell adhesion molecule-1 TDM therapeutic drug monitoring TNF tumor necrosis factor UC ulcerative colitis |
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