天星健骨方对佐剂性关节炎大鼠关节指数的影响 |
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引用本文: | 杨晓军,苗文丽,裴林,于素静,郑惠军.天星健骨方对佐剂性关节炎大鼠关节指数的影响[J].中医临床研究,2012,4(2):5-6. |
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作者姓名: | 杨晓军 苗文丽 裴林 于素静 郑惠军 |
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作者单位: | 1. 河北省中医药研究院,河北石家庄,050031 2. 唐山市第四医院,河北唐山,063000 3. 唐山市卫生监督所,河北唐山,063000 |
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基金项目: | 河北省科技支撑计划项目 |
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摘 要: | 目的:观察天星健骨方对佐剂性关节炎大鼠关节指数的影响。方法:采用注射弗氏完全佐剂制作大鼠佐剂性关节炎模型,将造模成功的50只SD大鼠随机分为模型组、天星健骨方低、中、高剂量组(0.4、0.6、0.8g/kg)、雷公藤多甙组(0.05g/kg)各10只,另设正常组(10只)。观察各组大鼠关节炎指数。结果:模型组和正常组比较,关节炎指数积分差异均有显著性(P0.01),各治疗组关节指数与模型组比较均有下降(P0.05或P0.01)。结论:天星健骨方能够减轻佐剂性关节炎模型大鼠的关节炎症状。
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关 键 词: | 天星健骨方 佐剂性关节炎 关节炎指数 |
Effects of Tianxing Jiangu recipe on joint index in AA rats |
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Abstract: | Objective: To observe effects of the recipe of Tianxing Jiangu on joint index in AA rats. Methods: Modeling AA rats, 50 SD rats were randomly divided into model group, low, medium and high dose group (0.4, 0.6, 0.8g/kg) of the recipe of Tianxing Jiangu, TWPgroup (0.05g/kg) and normal group (10 each), recording the rat arthritis indexes. Results: Comparing model group with normal group, AA index score had significant differences (P<0.01), articular index were decreased (P<0.05 or P<0.01) than the model group. Conclusion: The recipe of Tianxing Jiangu could reduce the arthritis symptoms of AA rats. |
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Keywords: | Tianxing jiangu recipe Adjuvant arthritis Arthritis index |
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