盐酸法舒地尔治疗急性脑梗死的临床疗效分析

目的观察法舒地尔治疗急性脑梗死的临床效果。方法选取2008年1-6月入住我院神经内科的急性脑梗死患者98例,随机分为治疗组和对照组,观察评价两组患者神经功能改善及病残程度的恢复情况。结果两组患者疗效明显,且未发现副作用,法舒地尔组患者在1周内神经功能恢复更明显。结论法舒地尔治疗急性脑梗死安全、有效,值得临床推广使用。

Therapeutic effect of fasudil hydrochloride on acute cerebral infarction

Objective To evaluate the efficacy and safety of fasudil hydrochloride(FSD)in patient with acute cerebral infarction(ACI).Methods 98 patients with ACI were randomized into 2 groups:FSD group(55 cases) and control group(43 cases).FSD group was received FSD injection with routine therapy:Salvia miltiorrhiza injection and aspirin.Control group was received routine therapy.The efficacy at the end of the 7 d therapy and in 21 d post the therapy was assessed using neurological functional deficit scores in terms of ESS and ability of daily life(ADL).Results Patients in both groups experienced significant improvement of ESS and ADL evaluation.But the improvement of FSD group patients is more significant than control group in the first week.No significant incidence of adverse events were reported in both groups.Conclusion This study showed that fasudil was a useful and safe drug for patients with acute cerebral infarction.