Three-dimensional visualization of protein interaction networks |
| |
Authors: | Han Kyungsook Byun Yanga |
| |
Affiliation: | School of Computer Science and Engineering, Inha University, Inchon 402-751, South Korea. khan@inha.ac.kr |
| |
Abstract: | Protein interaction networks provide us with contextual information within which protein function can be interpreted and will assist many biomedical studies. We have developed a new force-directed layout algorithm for visualizing protein interactions in three-dimensional space. Our algorithm divides nodes into three groups based on their interacting properties: bi-connected sub-graph in the center, terminal nodes at the outermost region, and the rest in between them. Experimental results show that our algorithm efficiently generates a clear and aesthetically pleasing drawing of large-scale protein interaction networks and that it is an order of magnitude faster than other force-directed layouts. |
| |
Keywords: | Protein-protein interactions Visualization Graph layout |
本文献已被 ScienceDirect PubMed 等数据库收录! |