罗氏血凝仪CoaguChek XS测定国际标准化比值准确性的临床研究

目的检测罗氏血凝仪CoaguChek XS测量指尖毛细血管国际标准化比值（INR）准确性,比较75%的酒精与碘伏分别进行皮肤消毒后对罗氏血凝仪CoaguChek XS测定INR结果的影响。方法选取2008年3-8月心内科80例住院病人,采用法国STAGO全自动凝血检测仪和床旁罗氏血凝仪测定INR;患者随机分为两组：A组40例采用75%酒精消毒法,B组40例采用碘伏消毒法。对静脉血与末梢血试纸测量得到的两组INR比值数据进行统计学处理。结果两种测量方法和消毒方法结果差异无统计学意义（P〉0.05）。结论罗氏血凝仪CoaguChek XS方便,快捷,对患者损伤小,能很快提供可靠数据;碘伏皮肤消毒不会影响快速血凝仪测量结果的准确性。

Accuracy of international normalized ratio detected with CoaguChek XS

Objective To compare the accuracy of international normalized ratio（INR） detected with CoaguChek XS（Roche Diagnostics,Basel Switzerland） in finger capillaries after sterilized with 75% alcohol and iodophor.Methods Eighty patients admitted to our hospital in March-August 2008 were divided into group A（n=40） and group B（n=40）.Their INR was detected with CoaguChek XS using two kinds of testing paper after sterilized with 75% alcohol and iodophor,respectively,and compared.Results No statistical difference was found in INR between the 2 detection methods and the two sterilization methods.Conclusion CoaguChek XS is more convenient and rapid to provide reliable data and leads to less injury to patients.Iodophor sterilization does not influence the accuracy of INR detected with CoaguChek XS.