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| 炮制对厚朴主要化学成分的影响 | |
| 引用本文： | 郭健,晏仁义,杨滨,王兴.炮制对厚朴主要化学成分的影响[J].中国实验方剂学杂志,2012,18(15):117-120. |
| 作者姓名： | 郭健 晏仁义 杨滨 王兴 |
| 作者单位： | 1. 中国中医科学院中药研究所,北京100700;西南交通大学生命科学与工程学院,成都610031 2. 中国中医科学院中药研究所,北京,100700 3. 西南交通大学生命科学与工程学院,成都,610031 |
| 基金项目： | "重大新药创制"科技重大专项(2009ZX09308-003); 国家中医药管理局中医药行业科研专项(200807020) |
| 摘 要： | 目的:考察炮制对厚朴中主要化学成分的影响.方法:以姜炒法对厚朴进行炮制,采用高效液相色谱法对厚朴炮制前后药材中木脂素类、苯乙醇苷类、生物碱类成分的含量进行测定;以气相色谱-质谱联用技术对挥发油成分进行分析.结果:与生厚朴相比,姜厚朴中厚朴酚、和厚朴酚、木兰花碱、挥发油成分的含量相近;苯乙醇苷类成分含量降低了约50％.结论:炮制会降低厚朴中苯乙醇苷类成分的含量. |
| 关 键 词： | 炮制 厚朴 化学成分定性定量分析 |
| 收稿时间： | 4/1/2012 12:00:00 AM |
Impact of Processing on Chemical Composition in Cortex Magnoliae Officinalis |
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| GUO Jian,YAN Ren-yi,YANG Bin and WANG Xing.Impact of Processing on Chemical Composition in Cortex Magnoliae Officinalis[J].China Journal of Experimental Traditional Medical Formulae,2012,18(15):117-120. | |
| Authors: | GUO Jian YAN Ren-yi YANG Bin and WANG Xing |
| Institution: | Institute of Chinese Materia Medica China Academy of Chinese Medical Sciences,Beijing 100700,China;Life Science and Engineering Southwest Jiaotong University,Chengdu 610031,China;Institute of Chinese Materia Medica China Academy of Chinese Medical Sciences,Beijing 100700,China;Institute of Chinese Materia Medica China Academy of Chinese Medical Sciences,Beijing 100700,China;Life Science and Engineering Southwest Jiaotong University,Chengdu 610031,China |
| Abstract: | Objective :To investigate the impact of processing on chemical composition in Cortex Magnoliae Officinalis. Method: Ginger juice was used to process the samples of Cortex Magnoliae Officinalis. An HPLC and a GC-MS method were established to analyze the changes of lignans, phenylpropanoid glycosides, alkaloids, volatile oil in processed and unprocessed samples. Result: Compared with unprocessed samples, no big difference was observed on the content of lignans, alkaloids and volatile oil, while the content of phenylpropanoid glycosides decreased by 50% in processed samples. Conclusion: The processing can reduce the content of phenylpropanoid glycosides in Cortex Magnoliae Officinalis. |
| Keywords: | processing Cortex Magnoliae Officinalis qualitative and quantitative analysis of chemical composition |
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