| Institution: | (1) Laboratory of Virology, Medical School, University of Crete, Heraklion, Crete, Greece;(2) Department of Applied Biochemistry & Immunology, Institute of Molecular Biology & Biotechnology, Vassilika Vouton, Heraklion, Crete, Greece;(3) Cardiology Department, University Hospital of Heraklion, Crete, Greece |
| Abstract: | Background Macrophages can produce vascular endothelial growth factor (VEGF) in response to hypoxia, transforming growth factor β1 (TGF-β1),
angiotensin II, basic fibroblast growth factor (bFGF), and interleukin-1. These factors have been found in the serum of coronary
artery disease (CAD) patients as well as in atherosclerotic lesions. The aim of the present study was to test the hypothesis
that the expression of VEGF, TGF-β1 and bFGF in peripheral monocytes and lymphocytes is related to CAD. |
