Long-term clinical outcome following coronary artery bypass grafting for isolated stenosis of the left anterior descending coronary artery |
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Authors: | Hennessy, T.G Codd, M.B Donnelly, S Hartigan, C McCann, H.A McCarthy, C Neligan, M Wood, A.E Luke, D McGovern, E Aherne, T Sugrue, D.D |
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Affiliation: | a Department of Clinical Cardiology, Dublin, Ireland b Departments of Epidemiology/Health Services Research, Mater Misericordiae Hospital (University College), Dublin, Ireland c Department of Cardiothoracic Surgery, Mater Misericordiae Hospital (University College), Dublin, Ireland d Department of Cardiothoracic Surgery, Cork Regional Hospital, Cork, Ireland |
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Abstract: | Aims To detail the clinical and angiographic profile, and long-termoutcome in consecutive patients with isolated stenosis of theleft anterior descending coronary artery undergoing bypass surgery. Methods A retrospective study of all patients (n=301) (January 1984December1990) and undergoing coronary artery bypass grafting for isolatedleft anterior descending disease, in the Irish Republic, wasperformed. Survival was compared with that of an exact age-and gender-matched cohort. Results Mean age was 53 (±9·3) years. There were 238 (79%)males. In 241 (80%) patients an internal thoracic arterial bypassgraft was used. Operative mortality was 1·3%. Of the280 (93%) patients alive (16 cardiac deaths) at 7·1 (±1·9)years, 105 (35%) had angina, 26 (9%) suffered an interval myocardialinfarction, and repeat revascularization was required on 29(10%). Female gender (P=0·002), pre-operative myocardialinfarction (P=0·02), significant diagonal disease (P=0·04)and postoperative myocardial infarction (P=0·0001) wereindependently associated with survival. Females were more likelyto develop congestive cardiac failure (P=0·01) or postoperativeangina (P=0·03) than their male counterparts. Conclusions Survivorship (97%) and event-free survival (96%) at 5 yearsfollowing coronary artery bypass grafting for isolated leftanterior descending coronary artery disease is excellent andequivalent to an age-matched and gender-matched cohort. |
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Keywords: | Bypass grafting coronary disease survival |
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