穴位埋线对慢性胃炎患者环核苷酸及胃肠激素的影响

目的:观察穴位埋线治疗慢性胃炎的临床疗效.方法:将70例慢性胃炎患者随机分为埋线组(36例)与针刺组(34例).主穴均为胃俞、中脘、足三里,分别进行埋线或针刺治疗,并观察血浆环磷酸腺苷(cAMP)、环磷酸鸟苷(cGMP)含量及胃泌素(Gas)、P物质(SP)含量的改变.结果:埋线组总有效率为88.89%优于针刺组76.47%(P＜0.05);两组各自治疗前后比较,血浆cAMP、cGMP、Gas、SP含量的改变差异具有非常显著性意义(P＜0.01);埋线组各项指标的改善程度均优于针刺组(P＜0.05).结论:穴位埋线治疗慢性胃炎有肯定疗效,通过调节环核苷酸和胃肠激素含量,从而改善了神经-内分泌-免疫调节功能.

Effects of thread embedding therapy on nucleotides and gastrointestinal hormones in the patient of chronic gastritis

Objective To observe therapeutic effect of thread embedding therapy on chronic gastritis. Methods Seventy cases of chronic gastritis were randomly divided into the treatment group (n=36) treated by thread embedding therapy and the control group (n = 34) by acupuncture. Weishu (BL 21), Zhongwan (CV 12) and Zusanli (ST 36) were selected as main points. And plasma contents of cAMP, cGMP, gastrin and substance P were observed before and after treatment. Results The total effective rate was 88. 89% in the treatment group and 76. 47% in the control group with a significant difference between the two groups (P<0. 05); there were significant differences before and after treatment in plasma contents of cAMP, cGMP, gastrin and substance P in the two groups (P< 0. 01), and the changes of these indexes in the treatment group were significantly superior to the control group (P< 0. 05). Conclusion Thread embedding therapy has a definite therapeutic effect on chronic gastritis and it can adjust nucleotides, gastrin and substance P to improve the functions of the nerve-endocrine-immunity network.