Chirale 3-Aminopropanole, 2. Mitt. N-Alkylierungsprodukte

Chiral 3-Aminopropanols, II: N-Alkylated Products From the racem. and optically active 3-aminopropanols 1a-1d the N-monomethyl compounds 3 are obtained via the urethanes 2 . Methylation of 1a-1d according to Eschweiler-Clarke or reaction with formaldehyde/NaBH₃CN yield the N-dimethyl compounds 4 . With acetone/NaBH₄ 1a-1d react to give the N-isopropyl compounds 6 .