| 墨旱莲水煎剂延缓衰老作用的研究 |
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| 引用本文： | 石变华,庄晓燕,白秀珍.墨旱莲水煎剂延缓衰老作用的研究[J].长治医学院学报,2009,23(5):331-333. |
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| 作者姓名： | 石变华 庄晓燕 白秀珍 |
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| 作者单位： | 1. 长治医学院心血管研究所,046000
2. 辽宁医学院 |
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| 基金项目： | 辽宁省教育厅资助项目 |
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| 摘 要： | 目的:研究墨旱莲的延缓衰老作用.方法:正常对照组小鼠每日腹腔注射生理盐水1 mg/10 g鼠重并同时灌胃与墨旱莲水煎剂等容量的生理盐水;单纯D-半乳糖损伤组小鼠每日腹腔注射与正常组等容量的D-半乳糖1 mg/10 g鼠重并同时灌胃与墨旱莲水煎剂等容量的生理盐水;墨旱莲水煎剂组腹腔注射与正常组等容量的D-半乳糖1 mg/10 g鼠重,同时分别灌胃墨旱莲水煎剂8 mg/g、16 mg/g、32 mg/g鼠重.第43 d取材测定SOD、MDA和GSH-PX.结果:与正常对照组相比单纯D-半乳糖损伤组的SOD和GSH-PX活性明显降低,MDA含量明显升高(P<0.05);与单纯D-半乳糖损伤组相比墨旱莲水煎剂组SOD和GSH-PX活性明显升高且MDA含量明显降低,并呈剂量依赖性(P<0.05～P<0.01).结论:墨旱莲水煎剂对D-半乳糖致衰老小鼠有延缓衰老作用.
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| 关 键 词： | 墨旱莲 衰老 |
To Study the Effect of Eclipta Alba Apozem on the Mice Induced Senilily by D-galactose |
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| Shi Bianhua,Zhuang Xiaoyan,Bai Xiuzheng.To Study the Effect of Eclipta Alba Apozem on the Mice Induced Senilily by D-galactose[J].Journal of Changzhi Medical College,2009,23(5):331-333. |
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| Authors: | Shi Bianhua Zhuang Xiaoyan Bai Xiuzheng |
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| Abstract: | Objective:The effect of delaying aging of Eclipta Alba apozem on the mice can be studied.Methods:The mice were divided into five groups and the four groups in them were injected with D-galactose by intraperitoneal every day.And the dosage is 1 mg/10 g weight.Another group was the normal one to compare with the four groups.The mice of the normal group were injected with brine by intraperitoneal every day.At the same time the three groups of the four groups were cured with different dosages of Eclipta Alba ap... |
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| Keywords: | SOD MDA GSH-PX |
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