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奋乃静与利培酮精神分裂症病人生活质量影响的比较研究
引用本文:任清涛,田明萍,等.奋乃静与利培酮精神分裂症病人生活质量影响的比较研究[J].中国行为医学科学,2002,11(1):32-33.
作者姓名:任清涛  田明萍
作者单位:山东淄博精神病医院 山东淄博255120 (任清涛,田明萍),山东淄博精神病医院 山东淄博255120(路英智)
摘    要:目的;探讨奋乃静与利培酮对精神分裂症病人生活质量的影响。方法:用阳性与阴性症状量表(PANSS)、生活质量综合评定问卷(GQOLI-74)分别评估患者的疗效及生活质量。结果:两组PANSS分值治疗前后均有显著差异, 而相互比较,则无显著性差异。而利培酮组的躯体健康维度、心理健康维度及社会功能维度 得分分别高于奋乃静组,均有显著性差异(P<0.01)。结论:奋乃静和利培桐对精神分裂症的疗效相当,但利培酮组的生活质量优于奋乃静组。

关 键 词:奋乃静  利培酮  精神分裂症  生活质量  比较研究
文章编号:1005-8559(2002)01-032-02
修稿时间:2001年3月23日

A comparative study between perphenazine and risperidone on the effect on the life quality of the patients with schizophrenia
REN Qing-tao,TIAN Ming-ping,LU Ying-Zhi.A comparative study between perphenazine and risperidone on the effect on the life quality of the patients with schizophrenia[J].Chinese Journal of Behavioral Medical Science,2002,11(1):32-33.
Authors:REN Qing-tao  TIAN Ming-ping  LU Ying-Zhi
Institution:REN Qing-tao,TIAN Ming-ping,LU Ying-Zhi. Mental Hospital of Zibo,Shan dong province,255120
Abstract:Objective To investigate the effect between perphenazine and risperidone on the life quality of patients with schizophrenia. Methods The patients with schizophrenia treated respectively by perphenazine and risperidone were compared. The efficacy was measured with the Positive and Negative Symptoms Scale (PANSS), while the life quality were evaluated with General Quality of Life Inventory-74 (GQOLI-74). Result After treatment, the scores of PANSS were both significantly decreased. The risperidone group had the better effect than the perphenazine group in the field of physical function, mental health and social function. The difference was significant (P<0.01). Conclusion The both drugs were similar in effect, but the patients with schizophrenia treated by risperidone had better life quality than that of perphenazine.
Keywords:Perphenazine  Risperidone  Schizophrenia  Life quality
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