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食管癌术后早期肠内营养支持对机体免疫功能的影响
引用本文:方东林,陈奇勋,严福来. 食管癌术后早期肠内营养支持对机体免疫功能的影响[J]. 肿瘤学杂志, 2000, 0(3)
作者姓名:方东林  陈奇勋  严福来
作者单位:浙江省余杭市第一人民医院!浙江余杭311000(方东林),浙江省肿瘤医院!浙江杭州310022(陈奇勋,严福来)
摘    要:[目的]观察食管癌术后早期肠内营养对机体免疫功能的影响。[方法]随机将50例食管癌病人分成两组 ,早期肠内营养(EEN)组(25例)和对照组(25例) ;分别在术前1天、术后1天、7天检测IgG、IgA、IgM及T细胞亚群、转铁蛋白。[结果]EEN组术后体液免疫(IgA、IgG)和T细胞亚群(CD3、CD 4、CD 4/CD 8)及转铁蛋白与对照组相比均有显著性差异(P<0 01) ,EEN组术后并发症有所减少。[结论]食管癌术后早期肠内营养能明显改善机体免疫功能。

关 键 词:食管肿瘤  肠内营养  免疫力  围手术期

The Impact on Immunity in Esophageal Cancer with Early Postoperative Enteral Nutrition
FANG Donglin,CHEN Qixun,YAN Fulai. The Impact on Immunity in Esophageal Cancer with Early Postoperative Enteral Nutrition[J]. Journal of Chinese Oncology, 2000, 0(3)
Authors:FANG Donglin  CHEN Qixun  YAN Fulai
Affiliation:FANG Donglin1,CHEN Qixun2,YAN Fulai2
Abstract:To evaluate the impact on immunity in esophageal cancer with early postoperative enteral nutrition(EEN)Fifty patients undergoing esophageal cancer surgery were divided into two groups randomlyTwentyfive cases in EEN group had a nasojejual tube inserted during the operationThe enteral feeding started within the first 24 hours postoperatively and continued for 7 consecutive daysTwentyfive cases in control group had venous nutrition for 7 daysThe levels of IgG,IgA,IgM,CD 3 CD 4,CD 4/CD 8 were tested in one day before operation and day 1,day 7 after operationIgA,IgG,T cell subgroup(CD 3,CD 4,CD 4/CD 8)and siderophilin were significantly different between 2 groups(P<001)EEN group had less postoperative complications[Conclusions]EEN could improve immmunity in esophageal cancer patients
Keywords:esophageal neoplasms  enteral nutrition  immunity  perioperation
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