阈值和阈值前期早产儿视网膜病变儿童视网膜电图观察

目的用全视野闪光视网膜电图（F-ERG）评价既往患阈值或阈值前期早产儿视网膜病变（ROP）JL童的视网膜功能。方法用F-ERG检查34例（68眼）既往有早产儿童，患阈值或阈值前期ROP者24例（48眼），出生年龄体重匹配的未患ROP者10例（20眼）。统计分析两组儿童暗视和明视各反应a波、b波潜伏期和振幅的差异。结果ROP组较对照组暗视视杆反应和最大混合反应a波、b波潜伏期延长，振幅降低，差异有统计学意义，P〈O．05。ROP组与对照组明视视锥反应a波、b波振幅和潜伏期无明显差别，P〉0．05。结论阈值或阈值前期ROP视网膜功能受到影响，以视杆细胞的功能降低为主。F-ERG是评价早产儿视网膜功能有效检测手段。

Full-field flash electroretinogram following up for children with history of pre-threshold or threshold ROP.

Objective To evaluate the retinal function by full-field flash electroretinogram （F-EGR） in children with history of pre-threshold or threshold ROP. Methods 24 children （48 eyes） with history of pre-threshold or threshold ROP and 10 children （20 eyes） with a history of premature birth but without ROP were examined by F-ERG. The latency and amplitude of a-wave and b-wave of various responses were analyzed. Results There was significant difference between ROP and control group in rod response, P 〈0.05, the latency was longer and the amplitude was low- er in ROP group. But there was no difference between ROP and control group in cone response, P 〉0.05. Conclusions The retinal function of ROP children are abnormal, which mainly in rod response. F-ERG is useful to evaluate retinal function in ROP children.