| Effect of Berberine on the mRNA Expression of Nitric Oxide Synthase （NOS） in Rat Corpus Cavernosum |
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| 引用本文： | 谭艳,明章银,汤强,蒋兆键,胡本容,向继洲. Effect of Berberine on the mRNA Expression of Nitric Oxide Synthase （NOS） in Rat Corpus Cavernosum[J]. 华中科技大学学报(医学英德文版), 2005, 25(2): 127-130. DOI: 10.1007/BF02873556 |
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| 作者姓名： | 谭艳 明章银 汤强 蒋兆键 胡本容 向继洲 |
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| 作者单位： | Department of Pharmacology，School of Basic Medical Sciences，Tongji Medical College，Huazhong University of Science and Technology，Wuhan 430030，China 2Department of Pharmacology，Yunyang Medical College，Shiyan 442000，China，Department of Pharmacology，School of Basic Medical Sciences，Tongji Medical College，Huazhong University of Science and Technology，Wuhan 430030，China，Department of Pharmacology，School of Basic Medical Sciences，Tongji Medical College，Huazhong University of Science and Technology，Wuhan 430030，China，Department of Pharmacology，School of Basic Medical Sciences，Tongji Medical College，Huazhong University of Science and Technology，Wuhan 430030，China，Department of Pharmacology，School of Basic Medical Sciences，Tongji Medical College，Huazhong University of Science and Technology，Wuhan 430030，China |
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| 基金项目： | This project was supported by a grant from the National Natural Science Foundation of China (No. 30171151). |
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| 摘 要： | Penile erection is a complex neurovascularprocess that involves relaxation of the corpus cav ernosum smooth muscle[1]. Relaxation of cavern osal smooth muscle leads to engorgement of bloodin the corpus cavernosum that results in an in crease in intracavernosal pressure and thus in tu mescence. Many studies have shown that nitric ox ide (NO) released from cavernous nerves and endo thelium is a key factor for penile erection. TheNO cGMP signaling pathway is…
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| 关 键 词： | 黄连素 mRNA 一氧化氮合酶 基因表达 小鼠 动物实验 |
| 收稿时间： | 2004-10-26 |
Effect of berberine on the mRNA expression of nitric oxide synthase (NOS) in rat corpus cavernosum |
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| Tan Yan,Ming Zhangyin,Tang Qiang,Jiang Zhaojian,Hu Benrong,Xiang Jizhou. Effect of berberine on the mRNA expression of nitric oxide synthase (NOS) in rat corpus cavernosum[J]. Journal of Huazhong University of Science and Technology. Medical sciences, 2005, 25(2): 127-130. DOI: 10.1007/BF02873556 |
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| Authors: | Tan Yan Ming Zhangyin Tang Qiang Jiang Zhaojian Hu Benrong Xiang Jizhou |
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| Affiliation: | 1. Department of Pharmacology, School of Basic Medical Sciences, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China;Department of Pharmacology, Yunyang Medical College, Shiyan 442000, China
2. Department of Pharmacology, School of Basic Medical Sciences, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China |
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| Abstract: | |
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| Keywords: | berberine nitric oxide synthase nitric oxide corpus cavernosum erectile dysfunction |
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