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正交法优选乳香最佳烘制工艺的研究
引用本文:胡素连,蒋孟良,陈卫红,蒋晓煌. 正交法优选乳香最佳烘制工艺的研究[J]. 中国药业, 2012, 21(1): 36-37
作者姓名:胡素连  蒋孟良  陈卫红  蒋晓煌
作者单位:1. 湖南省宁乡县人民医院药剂科,湖南长沙,410600
2. 湖南中医药大学,湖南长沙,410208
3. 湖南中医药大学第二附属医院,湖南长沙,410005
摘    要:目的 优选乳香烘制法的最佳炮制工艺.方法 以刺激性成分挥发油的总峰面积、峰数目和刺激性试验(兔眼充血与水肿)等4个评价指标,采用正交试验法,对温度、时间、放置厚度、药材直径等4个因素的水平进行优选.结果 乳香最佳烘制工艺为A2B3C1D1,即乳香直径0.5 cm,放置1 cm厚,120 ℃烘制2 h o结论优选出的炮制工艺合理、简单、可行、效率高,可为大规模生产提供参考依据.

关 键 词:乳香  烘制法  正交试验  中药炮制  气相色谱法  刺激试验

Study on the Best Baking Technology of Frankincense by Orthogonal Test
Hu Sulian,Jiang Mengliang,Chen Weihong,Jiang Xiaohuang. Study on the Best Baking Technology of Frankincense by Orthogonal Test[J]. China Pharmaceuticals, 2012, 21(1): 36-37
Authors:Hu Sulian  Jiang Mengliang  Chen Weihong  Jiang Xiaohuang
Affiliation:1.Ningxiang People's Hospital of Hunan,Changsha,Hunan,China 410600;2.Hunan University of Traditional Chinese Medicine,Changsha,Hunan,China 410208;3.The Second Affiliated Hospital of Hunan University of TCM,Changsha,Hunan,China 410005)
Abstract:Objective In order to select the best baking process of frankincense.Methods Taking the indexes of stimulating components,peak area and number of essential oil and irritant test(hyperemia and hydroncus in rabbit eye),baking temperature,time,thickness,diameter of Frankincense were optimizated by orthogonal design test.Results The best baking technology were A2B3C1D1,diameter of Frankinceuse 0.5 cm,thickness 1 cm,120 ℃baking for 2 h.Conclusion The baking method was reasonable,simple,feasible and high efficiency,it can provide a certain reference for mass-production.
Keywords:frankincense  baking  orthogonal test  processing  GC  irritant test
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