Studies on the alkaloid constituents of Evodia rutaecarpa (Juss) Benth var. bodinaieri (Dode) Huang and their acute toxicity in mice |
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| Authors: | Yang X-W Zhang H Li M Du L-J Yang Z Xiao S-Y |
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| Affiliation: | a State Key Laboratory of Natural & Biomimetic Drugs, School of Pharmaceutical Sciences, and Medical and Healthy Analysis Center, Peking University, Beijing, Chinab Laboratory of Pharmaceutical Science, Department of Biological Science and Biotechnology, Tsinghua University, Beijing, Chinac The Administrative Centre for China's Agenda 21, Ministry of Science and Technology, Beijing, China |
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| Abstract: | Six alkaloids (1-6) have been isolated from the fruits of Evodia rutaecarpa (Juss) Benth var. bodinaieri (Dode) Huang, two of which are new compounds, identified as 2-undecyl-4(1H)-quinolone (4) and 1-methyl-2-undecanone-10'-4(1H)-quinolone (5); the known compounds were identified as rutaecarpine (1), evodiamine (2), 1-methyl-2-undecyl-4(1H)-quinoline (3) and 2-undecanone-10'-4(1H)-quinolone (6). Compounds 1-5 were evaluated for their acute toxicity. |
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| Keywords: | Evodia rutaecarpa (Juss) Benth var. bodinaieri (Dode) Huang 2-Undecyl-4(1H)-quinolone 1-Methyl-2-undecanone-10'-4(1H)-quinolone |
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