对比分析头颈部鳞状细胞癌PET/CT与PET/MR特征

目的 探讨头颈部鳞状细胞癌（HNSCC）的PET/CT及PET/MR特征。方法 纳入未经抗肿瘤治疗的头颈部鳞状细胞癌患者40例，所有患者均接受PET/CT及头颈部MR检查。由2名观察者独立观察PET阳性病灶，包括阳性原发灶及阳性淋巴结；并对PET/CT、PET/MR T1WI及PET/MR T2WI的图像质量、融合准确度、病灶清晰度、病灶特征等进行评分。分析2名观察者间的一致性。结果 40例患者共90个PET阳性病灶，包括阳性原发灶40个、阳性淋巴结50个。PET/CT、PET/MR T1WI及PET/MR T2WI在图像质量及融合准确度方面差异均无统计学意义（P均>0.05）；在显示阳性原发灶及阳性淋巴结的清晰度方面，PET/MR T1WI及PET/MR T2WI均优于PET/CT（P均<0.05）。40个阳性原发灶中，PET/MR T2WI对29个原发灶的特征显示多于PET/CT，4个原发灶与PET/CT相仿，7个原发灶较PET/CT少。结论 PET/MR在HNSCC诊断中的应用是可行的，在显示头颈部局部病灶时较PET/CT更具优势。

Comparative analysis of PET/CT and PET/MR image characteristics of head and neck squamous cell carcinoma

Objective To investigate PET/CT and PET/MR characteristics of head and neck squamous cell carcinoma (HNSCC). Methods Totally 40 patients with HNSCC underwent whole body ¹⁸F-FDG PET/CT and MR scans of head and neck before anti-tumor treatment. PET positive lesions of HNSCC, including primary lesions and lymph nodes were evaluated by 2 radiologists independently. Then the imaging quality, fusion quality, lesion conspicuity and lesion characteristics were assessed based on PET/CT, PET/MR T1WI and PET/MR T2WI. Results Ninety PET positive lesions in all 40 patients were evaluated,including 40 primary lesions and 50 lymph nodes. Similar imaging quality and fusion quality of PET/CT, PET/MR T1WI and PET/MR T2WI were obtained without statistical difference (both P>0.05). For the lesion conspicuity, PET/MR T1WI and PET/MR T2WI demonstrated significantly better than PET/CT in positive primary lesions and lymph nodes (all P<0.05). For the characteristics of positive primary lesions, PET/MR T2WI provided more information than PET/CT in 29 lesions, equal to PET/CT in 4 lesions, and less than PET/CT in 7 lesions. Conclusion The application of PET/MR in HNSCC is feasible, being superior to PET/CT in indication of lesions in head and neck area.