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| 康柏西普联合激光治疗视网膜静脉阻塞继发黄斑水肿 | |
| 引用本文： | 刘慧峰,贾俊,姬明利,杨维佳,万鹏飞,韩双羽,何媛,王霞. 康柏西普联合激光治疗视网膜静脉阻塞继发黄斑水肿[J]. 国际眼科, 2017, 10(11): 2140-2143 |
| 作者姓名： | 刘慧峰 贾俊 姬明利 杨维佳 万鹏飞 韩双羽 何媛 王霞 |
| 作者单位： | 中国陕西省西安市,西安医学院第二附属医院眼科,中国陕西省西安市,西安医学院第二附属医院眼科,中国陕西省西安市,西安医学院第二附属医院眼科,中国陕西省西安市,西安医学院第二附属医院眼科,中国陕西省西安市,西安医学院第二附属医院眼科,中国陕西省西安市,西安医学院第二附属医院眼科,中国陕西省西安市,西安医学院第二附属医院眼科,中国陕西省西安市,西安医学院第二附属医院眼科 |
| 摘 要： | 目的：对比研究玻璃体腔注射康柏西普联合激光治疗与单纯激光治疗对视网膜静脉阻塞(retinal vein occlusion，RVO)继发黄斑水肿(macular edema，ME)的临床疗效。 方法：选取2014-10/2015-03我院临床检查确诊的RVO继发ME的患者48例53眼进行回顾性分析。其中玻璃体腔内注射康柏西普+激光治疗者28例31眼，为A组； 单纯激光治疗者20例22眼，为B组。观察治疗前和治疗后1wk，3mo最佳矫正视力(best corrected visual acuity，BCVA)及黄斑中心凹视网膜厚度(central macular thickness，CMT)的变化。 结果：随诊3mo，治疗后1wk时，A组和B组的平均BCVA分别是0.44±0.25、0.56±0.24； 平均CMT分别是330.50±121.71、354.67±102.79μm，两组患者BCVA和CMT较治疗前差异有统计学意义(P<0.05)； 而术后两组组间比较，差异无统计学意义(P>0.05)。在治疗后3mo时，A组和B组的平均BCVA分别是0.24±0.18、0.39±0.20； 平均CMT分别是252.62±83.01、332.67±102.33μm，两组患者与治疗前比较、两组组间比较，差异均有统计学意义(P<0.05)，且A组优于B组。 结论：玻璃体腔注射康柏西普联合激光和单纯激光治疗RVO继发性ME均有效，ME明显减轻，视力稳定并提高。但对于水肿严重的患者，玻璃体腔注射康柏西普先减轻视网膜水肿，再联合激光治疗疗效肯定，优于单纯激光治疗。 |
| 关 键 词： | 视网膜静脉阻塞 黄斑水肿 康柏西普注射液 视网膜光凝 |
| 收稿时间： | 2017-05-10 |
| 修稿时间： | 2017-09-22 |
Clinical observation of Conbercept intravitreal injection combined with retinal laser photocoagulation therapy on macular edema secondary to retinal vein occlusion |
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| Hui-Feng Liu,Jun Ji,Ming-Li Ji,Wei-Jia Yang,Peng-Fei Wan,Shuang-Yu Han,Yuan He and Xia Wang. Clinical observation of Conbercept intravitreal injection combined with retinal laser photocoagulation therapy on macular edema secondary to retinal vein occlusion[J]. International journal of ophthalmology, 2017, 10(11): 2140-2143 | |
| Authors: | Hui-Feng Liu Jun Ji Ming-Li Ji Wei-Jia Yang Peng-Fei Wan Shuang-Yu Han Yuan He Xia Wang |
| Affiliation: | Department of Ophthalmology, the Second Affiliated Hospital of Xi''an Medical University, Xi''an 710038, Shaanxi Province, China,Department of Ophthalmology, the Second Affiliated Hospital of Xi''an Medical University, Xi''an 710038, Shaanxi Province, China,Department of Ophthalmology, the Second Affiliated Hospital of Xi''an Medical University, Xi''an 710038, Shaanxi Province, China,Department of Ophthalmology, the Second Affiliated Hospital of Xi''an Medical University, Xi''an 710038, Shaanxi Province, China,Department of Ophthalmology, the Second Affiliated Hospital of Xi''an Medical University, Xi''an 710038, Shaanxi Province, China,Department of Ophthalmology, the Second Affiliated Hospital of Xi''an Medical University, Xi''an 710038, Shaanxi Province, China,Department of Ophthalmology, the Second Affiliated Hospital of Xi''an Medical University, Xi''an 710038, Shaanxi Province, China and Department of Ophthalmology, the Second Affiliated Hospital of Xi''an Medical University, Xi''an 710038, Shaanxi Province, China |
| Abstract: | |
| Keywords: | retinal vein occlusion macular edema conbercept ophthalmic injection retinal photocoagulation |
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