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西红花苷药理活性的研究进展
引用本文:韩宇,谢国勇,李冉,黄丽桃,秦民坚.西红花苷药理活性的研究进展[J].现代药物与临床,2017,32(9):1806-1814.
作者姓名:韩宇  谢国勇  李冉  黄丽桃  秦民坚
作者单位:中国药科大学中药资源学系,江苏南京,210009
基金项目:国家自然科学基金资助项目(81503220);江苏省自然科学基金资助项目(BK20150706);中央高校基本科研业务费培育项目(2015PY018)
摘    要:西红花苷又名藏红花素、藏红花苷或番红花苷,为西红花的主要活性成分。现代研究表明西红花苷对多种中枢神经系统和心血管系统疾病具有较好疗效,同时还具有抗癌、抗炎、抗氧化、保肝利胆及抗糖尿病等作用,此外长期以来还作为香料、染料和食品添加剂。为了充分开发利用西红花苷,对西红花苷近年来药理活性的研究热点进行综述。

关 键 词:西红花苷  药理活性  中枢神经系统疾病  心血管系统疾病
收稿时间:2017/6/16 0:00:00

Research progress on pharmacological activities of crocin
HAN Yu,XIE Guo-yong,LI Ran,HUANG Li-tao and QIN Min-jian.Research progress on pharmacological activities of crocin[J].Drugs & Clinic,2017,32(9):1806-1814.
Authors:HAN Yu  XIE Guo-yong  LI Ran  HUANG Li-tao and QIN Min-jian
Institution:Department of Resources Science of Traditional Chinese Medicines, China Pharmaceutical University, Nanjing 211198, China;Department of Resources Science of Traditional Chinese Medicines, China Pharmaceutical University, Nanjing 211198, China;Department of Resources Science of Traditional Chinese Medicines, China Pharmaceutical University, Nanjing 211198, China;Department of Resources Science of Traditional Chinese Medicines, China Pharmaceutical University, Nanjing 211198, China;Department of Resources Science of Traditional Chinese Medicines, China Pharmaceutical University, Nanjing 211198, China
Abstract:Crocin, also known as safflower, saffron glycosides or crocin, is the main active ingredient of Crocus sativus. The current studies have shown that crocin had a good effect for the variety of central nervous system and cardiovascular disease, also possessed anticancer, anti-inflammatory, antioxidant, protecting liver and anti-diabetic effects. Meantime, crocin has been widely used as a spice, food colorant and food additive for a long time. In order to advance the development and utilization of crocin, the pharmacological researches of crocin are reviewed in this paper.
Keywords:crocin  biological activities  central nervous system disease  cardiovascular disease
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