前列倍喜胶囊联合普适泰片治疗前列腺增生的疗效观察

目的探讨前列倍喜胶囊联合普适泰片治疗前列腺增生的临床效果。方法选取2015年2月—2017年2月靖边县人民医院泌尿外科收治的300例前列腺增生患者为研究对象,随机分为对照组和治疗组,每组各150例。对照组患者口服普适泰片,1片/次,2次/d。治疗组患者在对照组治疗基础上口服前列倍喜胶囊,6粒/次,3次/d。所有患者均连续治疗3个月。观察两组的临床疗效,比较两组治疗前后国际前列腺症状(IPSS)评分、生活质量(QOL)评分、残余尿量、前列腺体积和最大尿流率的变化情况。结果治疗后,对照组和治疗组的总有效率分别为84.0%、95.3%,两组总有效率比较差异有统计学意义(P0.05)。治疗后两组患者IPSS评分、QOL评分、残余尿量、前列腺体积均显著降低,最大尿流率显著升高,同组治疗前后差异有统计学意义(P0.05);治疗后治疗组IPSS评分、QOL评分、残余尿量、前列腺体积均显著低于对照组,最大尿流率高于对照组,两组比较差异有统计学意义(P0.05)。结论前列倍喜胶囊联合普适泰片治疗前列腺增生具有较好的临床疗效,可显著改善患者的临床症状,提高患者生活质量,具有一定的临床推广应用价值。

Clinical observation of Qianlie Beixi Capsules combined with Prostat Tablets in treatment of prostatic hyperplasia

Objective To explore the clinical effect of Qianlie Beixi Capsules combined with Prostat Tablets in treatment of prostatic hyperplasia. Methods Patients (300 cases) with prostatic hyperplasia in Department of Urinary Surgery of Jingbian County People''s Hospital from February 2015 to February 2017 were randomly divided into control (150 cases) and treatment (150 cases) groups. Patients in the control group were po administered with Prostat Tablets, 1 tablet/time, twice daily. Patients in the treatment group were po administered with Qianlie Beixi Capsules on the basis of the control group, 6 grains/time, three times daily. All patients were continuously treated for 3 months. After treatment, the clinical efficacy was evaluated, and the IPSS scores, QOL scores, residual urine volume, prostate volume and maximum urinary flow rate in two groups before and after treatment were compared. Results After treatment, the clinical efficacy in the control and treatment groups were 84.0% and 95.3%, respectively, and there was difference between two groups (P<0.05). After treatment, IPSS scores, QOL scores, residual urine volume, and prostate volume in two groups were significantly decreased, but maximum urinary flow rate significantly increased, and the difference was statistically significant in the same group (P<0.05). After treatment, IPSS scores, QOL scores, residual urine volume, and prostate volume in the treatment group were lower than those in the control group, maximum urinary flow rate was higher than that in the control group, and there was difference between two groups (P<0.05). Conclusion Qianlie Beixi Capsules combined with Prostat Tablets has a significant effect in treatment of prostatic hyperplasia, and can significantly improve the clinical symptoms, and improve the life quality, which has a certain clinical application value.